At the laboratory we have a wide range of assays to monitor pathways of donor directed reactivity. These assays focus on unraveling the T and B cell mediated immune responses and to study the mode of action of (novel) immunosuppressive drugs with the aim to titrate the immunosuppressive burden on our patients in such a way that side-effects (infections, malignancies, cardiovascular events) are kept at a minimum while at the same time rejection processes are prevented.
For more information on transplantation immunology applications within the Rotterdam Transplantation Laboratory please contact:
C.C. Baan, Prof. PhD